Article
The zebrafish diwanka gene controls an early step of motor growth cone migration.
Development (Cambridge, England) - 1 Aug 1999
Zeller J, Granato M
Abstract excerpt
During vertebrate embryogenesis different classes of motor axons exit the spinal cord and migrate on common axonal paths into the periphery. Surprisingly little is known about how this initial migration of spinal motor axons is controlled by external cues. Here, we show that the diwanka gene is required for growth cone migration of three identified subtypes of zebrafish primary motoneurons. In diwanka mutant...
Topics
- Animals
- Axons
- Cell Differentiation
- Cell Movement
- Cell Survival
- In Situ Hybridization
- Mesoderm
- Motor Neurons
- Mutation
- Neural Pathways
- Phenotype
- Somites
- Spinal Cord
- Zebrafish