Visualization of the Axonal Projection Pattern of Embryonic Motor Neurons in Drosophila.

doi:10.3791/55830

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Article

Visualization of the Axonal Projection Pattern of Embryonic Motor Neurons in Drosophila.

Journal of visualized experiments : JoVE - 16 Jun 2017

Jeong Sangyun

Abstract excerpt

The establishment of functional neuromuscular circuits relies on precise connections between developing motor axons and target muscles. Motor neurons extend growth cones to navigate along specific pathways by responding to a large number of axon guidance cues that emanate from the surrounding extracellular environment. Growth cone target recognition also plays a critical role in neuromuscular specificity. This...

Topics

Animals
Axons
Drosophila melanogaster
Embryo Culture Techniques
Genotype
Growth Cones
Immunohistochemistry
Microscopy
Motor Neurons
Muscles
Neuromuscular Junction

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Identifiers

PMID: 28654041
DOI: 10.3791/55830
PMCID: PMC5608453

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