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Article

CD26-mediated induction of EGR2 and IL-10 as potential regulatory mechanism for CD26 costimulatory pathway.

Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 2015

Hatano Ryo, Ohnuma Kei, Otsuka Haruna, Komiya Eriko, Taki Izumi, Iwata Satoshi, Dang Nam H, Okumura Ko, Morimoto Chikao

Abstract excerpt

CD26 is associated with T cell signal transduction processes as a costimulatory molecule, and CD26(+) T cells have been suggested to be involved in the pathophysiology of diverse autoimmune diseases. Although the cellular and molecular mechanisms involved in CD26-mediated T cell activation have been extensively evaluated by our group and others, potential negative feedback mechanisms to regulate CD26-mediated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25548232
DOI: 10.4049/jimmunol.1402143

Genes

EGR2

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