Article
ADIPOQ Genotypes, Adiponectin Isoforms, and Hypertension Risk in Pediatric Obesity.
Archives of medical research - 1 Jul 2026
Almeida Huemara Yuri, Cunha Warlley Rosa, Lanna Carla Márcia Moreira, de Miranda Josiane Aparecida, Lacchini Riccardo, Tanus-Santos José Eduardo, Luizon Marcelo Rizzatti, Belo Vanessa de Almeida
Abstract excerpt
BACKGROUND: Adiponectin (APN), especially its high molecular weight (HMW) isoform, is essential for metabolic regulation and cardiovascular protection. Variants in the ADIPOQ gene, including rs.266729 and rs.1501299, may influence APN levels and have been associated with obesity-related hypertension. AIMS: To evaluate the effects of ADIPOQ polymorphisms on plasma levels of total APN, the HMW isoform, and the...
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