Article
Hypoadiponectinemia is an independent risk factor for hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Jun 2004
Iwashima Yoshio, Katsuya Tomohiro, Ishikawa Kazuhiko, Ouchi Noriyuki, Ohishi Mitsuru, Sugimoto Ken, Fu Yuxiao, Motone Masaharu, Yamamoto Kouichi, Matsuo Akiko, Ohashi Koji, Kihara Shinji, Funahashi Tohru, Rakugi Hiromi, Matsuzawa Yuji, Ogihara Toshio
Abstract excerpt
Adiponectin is one of the key molecules in the metabolic syndrome, and its concentration is decreased in obesity, type-2 diabetes, and coronary artery disease. Genetic investigation has revealed that 2 polymorphisms (I164T and G276T) are related to adiponectin concentration and diabetes. To examine whether adiponectin affects hypertension genetically or biologically, we performed a case-control study. A total of...
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