Article
GATA5 loss-of-function mutation in familial dilated cardiomyopathy.
International journal of molecular medicine - 1 Mar 2015
Zhang Xian-Ling, Dai Neng, Tang Kai, Chen Yan-Qing, Chen Wei, Wang Juan, Zhao Cui-Mei, Yuan Fang, Qiu Xing-Biao, Qu Xin-Kai, Yang Yi-Qing, Xu Ya-Wei
Abstract excerpt
Dilated cardiomyopathy (DCM), the most common form of primary myocardial disease, is an important cause of sudden cardiac death and heart failure and is the leading indication for heart transplantation in children and adults worldwide. Recent studies have revealed a strong genetic basis for idiopathic DCM, with many distinct genes causally implicated. Nevertheless, DCM is a genetically heterogeneous disorder and...
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