Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel NKX2-5 loss-of-function mutation predisposes to familial dilated cardiomyopathy and arrhythmias

9 Dec 2014

Abstract excerpt

Dilated cardiomyopathy (DCM) is the most prevalent type of primary myocardial disease, which is the third most common cause of heart failure and the most frequent reason for heart transplantation. Aggregating evidence demonstrates that genetic risk factors are involved in the pathogenesis of idiopathic DCM. Nevertheless, DCM is of remarkable genetic heterogeneity and the genetic defects underpinning DCM in an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiomyopathy and Myosin Studies
Share to Congenital heart defects research
Share to RNA and protein synthesis mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25503402
DOI: 10.3892/ijmm.2014.2029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel NKX2-5 loss-of-function mutation predisposes to familial dilated cardiomyopathy and arrhythmiasPMID 25503402Read ↗

Prevalence and Spectrum of NKX2-5 Mutations Associated With Sporadic Adult-Onset Dilated Cardiomyopathy.Semantic proximity Read ↗

A novel NKX2.5 loss-of-function mutation responsible for familial atrial fibrillation.Semantic proximity Read ↗

Functional characterization of a novel mutation in NKX2-5 associated with congenital heart disease and adult-onset cardiomyopathy.Semantic proximity Read ↗

Mutational spectrum of the NKX2-5 gene in patients with lone atrial fibrillation.Semantic proximity Read ↗

Mutation of a common amino acid in NKX2.5 results in dilated cardiomyopathy in two large families.Semantic proximity Read ↗

Prevalence and spectrum of Nkx2.5 mutations associated with idiopathic atrial fibrillation.Semantic proximity Read ↗

TBX5 loss-of-function mutation contributes to familial dilated cardiomyopathy.Semantic proximity Read ↗

Identification and functional characterization of KLF5 as a novel disease gene responsible for familial dilated cardiomyopathy.Semantic proximity Read ↗

GATA4 loss-of-function mutation underlies familial dilated cardiomyopathy.Semantic proximity Read ↗

GATA5 loss-of-function mutation in familial dilated cardiomyopathy.Semantic proximity Read ↗

A novel GATA4 loss-of-function mutation responsible for familial dilated cardiomyopathy.Semantic proximity Read ↗

Functional analysis of novel genetic variants of NKX2-5 associated with nonsyndromic congenital heart disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.