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Article

GATA4 loss-of-function mutation underlies familial dilated cardiomyopathy.

Biochemical and biophysical research communications - 4 Oct 2013

Li Ruo-Gu, Li Li, Qiu Xing-Biao, Yuan Fang, Xu Lei, Li Xin, Xu Ying-Jia, Jiang Wei-Feng, Jiang Jin-Qi, Liu Xu, Fang Wei-Yi, Zhang Min, Peng Lu-Ying, Qu Xin-Kai, Yang Yi-Qing

Abstract excerpt

The cardiac transcription factor GATA4 is essential for cardiac development, and mutations in this gene have been implicated in a wide variety of congenital heart diseases in both animal models and humans. However, whether mutated GATA4 predisposes to dilated cardiomyopathy (DCM) remains unknown. In this study, the whole coding region and splice junction sites of the GATA4 gene was sequenced in 110 unrelated...

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Source

Identifiers

PMID: 24041700
DOI: 10.1016/j.bbrc.2013.09.023

Genes

GATA4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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