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Article

A neutrality test for detecting selection on DNA methylation using single methylation polymorphism frequency spectrum.

Genome biology and evolution - 23 Dec 2014

Wang Jun, Fan Chuanzhu

Abstract excerpt

Inheritable epigenetic mutations (epimutations) can contribute to transmittable phenotypic variation. Thus, epimutations can be subject to natural selection and impact the fitness and evolution of organisms. Based on the framework of the modified Tajima's D test for DNA mutations, we developed a neutrality test with the statistic "D(m)" to detect selection forces on DNA methylation mutations using single...

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Identifiers

PMID: 25539727
DOI: 10.1093/gbe/evu271
PMCID: PMC4316624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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