Article

Mutation saturation for fitness effects at human CpG sites

2021-06-02

Abstract excerpt

Whole exome sequences have now been collected for millions of humans, with the related goals of identifying pathogenic mutations in patients and establishing reference repositories of data from unaffected individuals. As a result, we are approaching an important limit, in which datasets are large enough that, in the absence of natural selection, every highly mutable site will have experienced at least one mutation...

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Literature Corpus work: 94f54be0-154f-5851-a552-953871ebc4c3
DOI: 10.1101/2021.06.02.446661

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