Article
MACE: mutation-oriented profiling of chemical response and gene expression in cancers.
Bioinformatics (Oxford, England) - 1 May 2015
Jeong Euna, He Ningning, Park Hyerin, Song Mee, Kim Nayoung, Lee Seongjoon, Yoon Sukjoon
Abstract excerpt
SUMMARY: The mutational status of specific cancer lineages can affect the sensitivity to or resistance against cancer drugs. The MACE database provides web-based interactive tools for interpreting large chemical screening and gene expression datasets of cancer cell lines in terms of mutation and lineage categories. GI50 data of chemicals against individual NCI60 cell lines were normalized and organized to...
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