Article
Methylenetetrahydrofolate reductase C677T polymorphism in patients with lung cancer in a Korean population.
BMC medical genetics - 22 Feb 2011
Cui Lian-Hua, Shin Min-Ho, Kim Hee Nam, Song Hye-Rim, Piao Jin-Mei, Kweon Sun-Seog, Choi Jin-Su, Yun Woo-Jun, Kim Young-Chul, Oh In-Jae, Kim Kyu-Sik
Abstract excerpt
BACKGROUND: This study was designed to investigate an association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and the risk of lung cancer in a Korean population. METHODS: We conducted a large-scale, case-control study involving 3938 patients with newly diagnosed lung cancer and 1700 healthy controls. Genotyping was performed with peripheral blood DNA for MTHFR C677T polymorphisms....
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