Quantitative assessment of the effect of MTHFR polymorphisms on the risk of lung carcinoma.

doi:10.1007/s11033-011-1439-1

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Article

Quantitative assessment of the effect of MTHFR polymorphisms on the risk of lung carcinoma.

Molecular biology reports - 1 May 2012

Zhang Yao, Chen Guo Qiang, Ji Yong, Huang Bin, Shen Wei Sheng, Deng Li Chun, Xi Lei, Cao Xiang Ming

Abstract excerpt

Published studies on the relationships between 5,10-methylenetetrahydrofolate reductase (MTHFR) polymorphisms and lung cancer risk have been conflicting. To derive a more precise estimation of the relationship, a meta-analysis was performed. Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated to assess the association between MTHFR C677T and A1298C polymorphisms and lung cancer risk. A total of...

Topics

Confidence Intervals
Ethnicity
Female
Genetic Association Studies
Genetic Predisposition to Disease
Humans
Lung Neoplasms
Male
Methylenetetrahydrofolate Reductase (NADPH2)
Odds Ratio
Polymorphism, Single Nucleotide
Publication Bias
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 22215214
DOI: 10.1007/s11033-011-1439-1

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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