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Article

Methylenetetrahydrofolate reductase 677TT genotype might be associated with an increased lung cancer risk in Asians.

Gene - 15 Feb 2013

Liu Zheng-Bing, Wang Li-Ping, Shu Jun, Jin Cheng, Lou Zhi-Xia

Abstract excerpt

BACKGROUND: The association between methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorphism and lung cancer risk has been studied in various populations with conflicting results. The aim of this study was to assess the association strength by a meta-analysis of published studies. METHODS: We searched PubMed and Chinese Biomedical (CBM) databases for relevant literatures published by July 18, 2012. Pooled...

Topics

Alleles
Asian People
Codon
Genetic Predisposition to Disease
Genotype
Humans
Lung Neoplasms
Methylenetetrahydrofolate Reductase (NADPH2)
Polymorphism, Single Nucleotide
Publication Bias
White People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23237779
DOI: 10.1016/j.gene.2012.11.036

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-23237779-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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