Article
KRAS mutation correlates with accelerated metastatic progression in patients with colorectal liver metastases.
Annals of surgical oncology - 1 Feb 2010
Nash Garrett M, Gimbel Mark, Shia Jinru, Nathanson Daniel R, Ndubuisi MacKevin I, Zeng Zhao-Shi, Kemeny Nancy, Paty Philip B
Abstract excerpt
BACKGROUND: Observational studies of patients with primary colorectal cancer have identified KRAS mutation as a marker of poor prognosis. To examine more directly whether KRAS mutations are associated with accelerated metastatic progression, we evaluated KRAS mutation as well as Ki-67 expression...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.