Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The frequencies of haplotypes defined by three polymorphisms of the IL-31 gene: -1066, -2057, and IVS2+12 in Polish patients with atopic dermatitis.

International journal of dermatology - 1 Jan 2015

Sokołowska-Wojdyło Małgorzata, Gleń Jolanta, Zabłotna Monika, Rębała Krzysztof, Trzeciak Magdalena, Sikorska Monika, Ruckemann-Dziurdzińska Katarzyna, Nedoszytko Boguslaw, Florek Aleksandra, Nowicki Roman

Abstract excerpt

BACKGROUND: Severe pruritus is one of the cardinal symptoms of atopic dermatitis (AD). Recently, the interleukin (IL)-31 cytokine has been implicated in the induction and maintenance of severe pruritus and chronic skin inflammation in several pruritic skin diseases, including AD. OBJECTIVE: We aimed to investigate the association of the IL-31 gene haplotypes with pruritus and severity of AD, as well as their...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Dermatitis, Atopic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Interleukins

Share to Poland

Share to Pruritus

Share to Severity of Illness Index

Share to Young Adult

Source

Identifiers

PMID: 25534405
DOI: 10.1111/ijd.12666

Genes

GAA
AGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The frequencies of haplotypes defined by three polymorphisms of the IL-31 gene: -1066, -2057, and IVS2+12 in Polish patients with atopic dermatitis.PMID 25534405Read ↗

A common haplotype of the IL-31 gene influencing gene expression is associated with nonatopic eczema.Semantic proximity Read ↗

Interleukin-31 Polymorphisms and Serum IL-31 Level in Patients with Mastocytosis: Correlation with Clinical Presen-tation and Pruritus.Semantic proximity Read ↗

The association of interleukin-31 polymorphisms with interleukin-31 serum levels and risk of systemic lupus erythematosus.Semantic proximity Read ↗

The molecular basis for IL-31 production and IL-31-mediated itch transmission: from biology to drug developmentSemantic proximity Read ↗

Association of vitamin D receptor gene polymorphisms with severe atopic dermatitis in adults.Semantic proximity Read ↗

Functional regulation of interleukin-31 production by its genetic polymorphism in patients with extrinsic atopic dermatitis.Semantic proximity Read ↗

Il-31 does not correlate to pruritus related to early stage cutaneous T-cell lymphomas but is involved in pathogenesis of the disease.Semantic proximity Read ↗

Exploring the Impact of IL-33 Gene Polymorphism (rs1929992) on Susceptibility to Chronic Urticaria and its Association with Serum Interleukin-33 levelsSemantic proximity Read ↗

IL31 identified as a key genetic risk factor for prurigo nodularis.Semantic proximity Read ↗

The role of interleukin-31 in human allergic diseaseSemantic proximity Read ↗

Exploring the Impact of IL-33 Gene Polymorphism (rs1929992) on Susceptibility to Chronic Spontaneous Urticaria and Its Association with Serum Interleukin-33 Levels.Semantic proximity Read ↗

The IL-33/IL-31 Axis in Allergic and Immune-Mediated DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.