Article
Il-31 does not correlate to pruritus related to early stage cutaneous T-cell lymphomas but is involved in pathogenesis of the disease.
Acta dermato-venereologica - 1 Mar 2015
Malek Marta, Gleń Jolanta, Rębała Krzysztof, Kowalczyk Anna, Sobjanek Michal, Nowicki Roman, Ruckemann-Dziurdzińska Katarzyna, Sokołowska-Wojdyło Małgorzata
Abstract excerpt
Mycosis fungoides (MF) and Sézary syndrome (SS) belong to the group of primary cutaneous T-cell lymphomas (CTCL). Regardless of the stage of the disease, patients with MF and SS can suffer from chronic pruritus. The aim of the study was to investigate the correlation between the interleukin 31 (IL-31) serum level, the degree of pruritus and CTCL severity; and to compare the frequency of IL-31 gene polymorphisms...
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