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Article

The association of interleukin-31 polymorphisms with interleukin-31 serum levels and risk of systemic lupus erythematosus.

Rheumatology international - 1 Jun 2016

Huang Hua-Tuo, Chen Jian-Ming, Guo Jing, Lan Yan, Wei Ye-Sheng

Abstract excerpt

Interleukin-31 (IL-31) is the most recently discovered member of the gp130/IL-6 cytokine family which is produced mainly by activated Th2 cells. IL-31 was proved to play a crucial role in autoimmune and inflammatory diseases such as atopic dermatitis, asthma, cutaneous T cell lymphomas, Kawasaki disease and allergic rhinitis. Previous studies have identified that IL-31 could significantly induce the release of...

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PMID: 26769434
DOI: 10.1007/s00296-016-3422-6

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