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Article

IL31 identified as a key genetic risk factor for prurigo nodularis.

The Journal of allergy and clinical immunology - 1 Nov 2025

Patrick Matthew T, Wu Yuntian, Zhong Xue, Li Qinmengge, Julia Valérie, Li Bingshan, Gudjonsson Johann E, Tsoi Lam C

Abstract excerpt

BACKGROUND: Although previous studies have suggested that genetic risk factors can contribute to the development of prurigo nodularis (PN), little is known about the specific variants involved. OBJECTIVE: We aimed to test which genetic variants increase predisposition to PN by conducting a large genome-wide association study. METHODS: Five separate cohorts (4239 case patients with PN and 583,544 controls) were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40651664
DOI: 10.1016/j.jaci.2025.06.031
PMCID: PMC13135726

Genes

IL31

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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