Article
Interleukin-31 Polymorphisms and Serum IL-31 Level in Patients with Mastocytosis: Correlation with Clinical Presen-tation and Pruritus.
Acta dermato-venereologica - 4 Jan 2017
Lange Magdalena, Gleń Jolanta, Zabłotna Monika, Nedoszytko Bogusław, Sokołowska-Wojdyło Małgorzata, Rębała Krzysztof, Ługowska-Umer Hanna, Niedoszytko Marek, Górska Aleksandra, Sikorska Monika, Zawadzka Agata, Nowicki Roman
Abstract excerpt
Data on interleukin-31 (IL-31) involvement in the patho-genesis of mastocytosis, and its impact on pruritus development in the disease, are limited. The aim of this study was to analyse distinct IL-31 gene polymorphisms in 127 patients (age 0.5-76 years) with mastocytosis and their correlation with clinical presentation, pruritus and serum IL-31 levels. In patients with mastocytosis, the frequency of IL-31...
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