Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Breast cancer risk genes affecting individual radiosensitivity.

Scientific reports - 14 Jun 2026

Vogel Ramona K G, Amann Niklas, Kassem Tara Zuhair, Gaß Paul, Mayo Theresa, Woltereck Felix, Hack Carolin C, Fietkau Rainer, Corradini Stefanie, Distel Luitpold, Kuhlmann Lukas C F

Abstract excerpt

Increased radiosensitivity can cause adverse radiotherapy effects. Heterozygote variants in breast cancer risk genes increase cancer risk and may affect radiosensitivity. This study assessed their impact on individual radiosensitivity to determine the radiation risk for gene carriers. Radiosensitivity was analyzed in 273 patients with breast cancer risk gene variants. Using fluorescence in situ hybridization...

Topics

Join the communities discussing this publication.

Aged
Breast Neoplasms
Case-Control Studies
Chromosome Aberrations
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

In Situ Hybridization, Fluorescence

Radiation Tolerance

Source

Open in PubMed Open full text

Identifiers

PMID: 42289459
DOI: 10.1038/s41598-026-57275-x
PMCID: PMC13265738

Genes

BARD1
BRCA1
RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Breast cancer risk genes affecting individual radiosensitivity.PMID 42289459Read ↗

Ionizing radiation-induced DNA injury and damage detection in patients with breast cancerSemantic proximity Read ↗

ATM Variants in Breast Cancer: Implications for Breast Radiation Therapy Treatment RecommendationsSemantic proximity Read ↗

Radiation biology and oncology in the genomic eraSemantic proximity Read ↗

Genetic variation in radiation-induced cell death.Semantic proximity Read ↗

Heritability of cellular radiosensitivity: a marker of low-penetrance predisposition genes in breast cancer?Semantic proximity Read ↗

Polymorphisms in double strand break repair related genes influence radiosensitivity phenotype in lymphocytes from healthy individuals.Semantic proximity Read ↗

Chromosomal radiosensitivity and low penetrance predisposition to cancer.Semantic proximity Read ↗

[Genetic bases of the radiosensitivity of breast cancer].Semantic proximity Read ↗

Molecular contribution of BRCA1 and BRCA2 to genome instability in breast cancer patients: review of radiosensitivity assaysSemantic proximity Read ↗

Polymorphism of DNA repair genes in breast cancerSemantic proximity Read ↗

Radiotherapy and genetic predisposition to breast cancer.Semantic proximity Read ↗

Polymorphisms in DNA repair genes, medical exposure to ionizing radiation, and breast cancer risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.