Article
Genetics of HDL regulation in humans.
Current opinion in lipidology - 1 Jun 2003
Miller Michael, Rhyne Jeffrey, Hamlette Steven, Birnbaum Josh, Rodriguez Anabelle
Abstract excerpt
PURPOSE OF REVIEW: To review gene regulation of HDL-cholesterol and discuss molecular abnormalities in HDL candidate genes that may lead to human pathologic states. RECENT FINDINGS: The inverse association between HDL-cholesterol and vascular disease, especially coronary heart disease, has long been recognized, but understanding gene regulation of HDL in humans gained considerable momentum following the...
Topics
- ATP Binding Cassette Transporter 1
- ATP-Binding Cassette Transporters
- Animals
- Apolipoprotein A-I
- CD36 Antigens
- Carrier Proteins
- Cholesterol Ester Transfer Proteins
- Cholesterol, HDL
- Down-Regulation
- Glycoproteins
- Humans
- Hypercholesterolemia
- Lipoprotein Lipase
- Liver
- Membrane Proteins
- Mutation
- Receptors, Immunologic
- Receptors, Lipoprotein