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Article

Sunitinib-induced severe toxicities in a Japanese patient with the ABCG2 421 AA genotype.

BMC cancer - 16 Dec 2014

Miura Yuji, Imamura Chiyo K, Fukunaga Koya, Katsuyama Yoshihiko, Suyama Koichi, Okaneya Toshikazu, Mushiroda Taisei, Ando Yuichi, Takano Toshimi, Tanigawara Yusuke

Abstract excerpt

BACKGROUND: Sunitinib is a multi-targeted receptor tyrosine kinase inhibitor that acts against receptors for vascular endothelial growth factor and platelet-derived growth factor. Common toxicities of sunitinib treatment include hypertension, hand-foot syndrome, vomiting, and diarrhea, and the pr...

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Source

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Identifiers

PMID: 25515134
DOI: 10.1186/1471-2407-14-964
PMCID: PMC4301945

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25515134-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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