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Article

Sulforaphane enhances progerin clearance in Hutchinson-Gilford progeria fibroblasts.

Aging cell - 1 Feb 2015

Gabriel Diana, Roedl Daniela, Gordon Leslie B, Djabali Karima

Abstract excerpt

Hutchinson-Gilford progeria syndrome (HGPS, OMIM 176670) is a rare multisystem childhood premature aging disorder linked to mutations in the LMNA gene. The most common HGPS mutation is found at position G608G within exon 11 of the LMNA gene. This mutation results in the deletion of 50 amino acids...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25510262
DOI: 10.1111/acel.12300
PMCID: PMC4326906

Genes

SFN
LMNA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25510262-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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