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Article

Hematopoietic-specific Rho GTPases Rac2 and RhoH and human blood disorders.

Experimental cell research - 10 Sept 2013

Troeger Anja, Williams David A

Abstract excerpt

The small guanosine triphosphotases (GTPases) Rho proteins are members of the Ras-like superfamily. Similar to Ras, most Rho GTPases cycle between active GTP-bound, and inactive GDP-bound conformations and act as molecular switches that control multiple cellular functions. While most Rho GTPases are expressed widely, the expression of Rac2 and RhoH are restricted to hematopoietic cells. RhoH is an atypical GTPase...

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Source

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Identifiers

PMID: 23850828
DOI: 10.1016/j.yexcr.2013.07.002
PMCID: PMC3997055

Genes

RAC2
RHOH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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