Article
IL36G genetic variant is independently associated with susceptibility, severity and joint involvement in psoriasis.
Molecular immunology - 1 Jul 2023
Moreira Cássio Rafael, de Alcântara Camila Cataldi, Flauzino Tamires, Martin Ligia Marcia Mario, Lozovoy Marcell Alysson Batisti, Reiche Edna Maria Vissoci, Simão Andréa Name Colado
Abstract excerpt
Psoriasis (PsO) is a chronic, immune-mediated, inflammatory and polygenic dermatosis associated with both physical and psychological burden that can be triggered by injury, trauma, infections and medications. The etiology of PsO is not fully elucidated but genetic, epigenetic and environmental factors are all likely to play a role. A case-control study was carried out to evaluate the frequency of the IL36G C>T...
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