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Article

The association of the MTHFR c.1625A>C genetic variant with the risk of congenital heart diseases in the Chinese.

Genetic testing and molecular biomarkers - 1 Jan 2015

Wang Yuting, Sun Lei, Du Weina, Song Shuang, Wang Shuo, Jiang Weiju, Huang Tianchu, Li Hui

Abstract excerpt

The purpose of this study is to investigate the association of methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms with the risk of congenital heart diseases (CHD). The genotypes of the MTHFR genetic variant were determined by the polymerase chain reaction-restriction fragment length polymorphism and DNA sequencing methods. Our data suggested that the allelic and genotypic frequencies of CHD patients...

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Source

Open in PubMed Open full text

Identifiers

PMID: 25494855
DOI: 10.1089/gtmb.2014.0253
PMCID: PMC4278078

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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