Article
Dopaminergic gene polymorphisms affect long-term forgetting in old age: further support for the magnification hypothesis.
Journal of cognitive neuroscience - 1 Apr 2013
Papenberg Goran, Bäckman Lars, Nagel Irene E, Nietfeld Wilfried, Schröder Julia, Bertram Lars, Heekeren Hauke R, Lindenberger Ulman, Li Shu-Chen
Abstract excerpt
Emerging evidence from animal studies suggests that suboptimal dopamine (DA) modulation may be associated with increased forgetting of episodic information. Extending these observations, we investigated the influence of DA-relevant genes on forgetting in samples of younger (n = 433, 20-31 years) and older (n = 690, 59-71 years) adults. The effects of single nucleotide polymorphisms of the DA D2 (DRD2) and D3...
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