Article
Association between polymorphisms in renin-angiotensin system genes and primary ovarian insufficiency in Korean women.
Menopause (New York, N.Y.) - 1 May 2013
Jung Yong Wook, Jeon Young Joo, Park Hye Mi, Lee Bo Eun, Rah Hyungchul, Lee Woo Sik, Yoon Tae Ki, Kim Nam Keun
Abstract excerpt
OBJECTIVE: The purpose of this study was to evaluate the relationship between angiotensin-converting enzyme (ACE; insertion/deletion), angiotensinogen (AGT M235T), and angiotensin II type 1 receptor (AT1R 1166A>C) and the prevalence of primary ovarian insufficiency (POI) in Korean women. METHODS: A total of 133 women with POI and 238 controls were genotyped for polymorphic sites in each gene using polymerase...
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