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Tumor necrosis factor-alpha promoter polymorphisms are associated with idiopathic primary ovarian insufficiency in Korean women.

Fertility and sterility - 1 Nov 2012

Kim Ji Hyang, Jeon Young Joo, Rah Hyungchul, Lee Bo Eun, Choi Dong Hee, Lee Woo Sik, Kim Nam Keun

Abstract excerpt

OBJECTIVE: To investigate the possible association between primary ovarian insufficiency (POI) and TNF-α gene polymorphisms in Korean women. DESIGN: Case-control study. SETTING: An urban university-based hospital in South Korea. PATIENT(S): A cohort of 135 Korean POI patients and 236 controls. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): We analyzed TNF-α gene variants of all participants using the polymerase...

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PMID: 22884017
DOI: 10.1016/j.fertnstert.2012.07.1111

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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