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Article

In vitro selection of HIV-1 CRF08_BC variants resistant to reverse transcriptase inhibitors.

AIDS research and human retroviruses - 1 Feb 2015

Wu Hao, Zhang Xiao-Min, Zhang Hao-Jie, Zhang Qiwei, Chen Zhiwei, Huang Jian-Dong, Lee Shui-Shan, Zheng Bo-Jian

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) circulating recombinant form 08_BC (CRF08_BC), carrying the recombinant reverse transcriptase (RT) gene from subtypes B and C, has recently become highly prevalent in Southern China. As the number of patients increases, it is important to characterize the drug resistance mutations of CRF08_BC, especially against widely used antiretrovirals. In this study, clinically...

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Identifiers

PMID: 25482475
DOI: 10.1089/AID.2013.0211
PMCID: PMC4313396

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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