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Article

Characterization of the E138K resistance mutation in HIV-1 reverse transcriptase conferring susceptibility to etravirine in B and non-B HIV-1 subtypes.

Antimicrobial agents and chemotherapy - 1 Feb 2011

Asahchop Eugene L, Oliveira Maureen, Wainberg Mark A, Brenner Bluma G, Moisi Daniela, Toni Thomas d'Aquin, Tremblay Cecile L

Abstract excerpt

We have selected for resistance to etravirine (ETR) and efavirenz (EFV) in tissue culture using three subtype B, three subtype C, and two CRF02_AG clinical isolates, grown in cord blood mononuclear cells. Genotypic analysis was performed at baseline and at various weeks of selection. Phenotypic resistance in regard to ETR, EFV, and nevirapine (NVP) was evaluated at weeks 25 to 30 for all ETR-selected viruses and...

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Identifiers

PMID: 21135184
DOI: 10.1128/AAC.01192-10
PMCID: PMC3028807

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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