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Article

[Replication of the subgenomic hepatitis C virus replicon in the presence of the NS3 protease inhibitors: a stochastic model].

Biofizika - 1 Jan 2000

Ivanisenko N V, Mishchenko E L, Akberdin I R, Demenkov P S, Likhoshvai V A, Kozlov K N, Todorov D I, Samsonova M G, Samsonov A M, Kolchanov N A, Ivanisenko V A

Abstract excerpt

The hepatitis C virus (HCV) belongs to Flaviviridae family and causes hazardous liver diseases leading frequently to cirrhosis and hepatocellular carcinoma. HCV is able to rapidly acquire drug resistance and for this reason there is currently no effective anti-HCV therapy in spite of appearance of new potential drugs. Mathematical models are relevant to predict the efficacy of potential drugs against virus or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25481944

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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