Article
Structural insights into Escherichia coli polymyxin B resistance protein D with X-ray crystallography and small-angle X-ray scattering.
BMC structural biology - 5 Dec 2014
Jo Hunho, Jeong Eui Young, Jeon Jinseong, Ban Changill
Abstract excerpt
BACKGROUND: Polymyxin B resistance protein D (PmrD) plays a key role in the polymyxin B-resistance pathway, as it is the signaling protein that can act as a specific connecter between PmrA/PmrB and PhoP/PhoQ. We conducted structural analysis to characterize Escherichia coli (E. coli) PmrD, which exhibits different features compared with PmrD in other bacteria. RESULTS: The X-ray crystal structure of E. coli PmrD...
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