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Article

Predictive and prognostic markers in the treatment of metastatic colorectal cancer (mCRC): personalized medicine at work.

Hematology/oncology clinics of North America - 1 Feb 2015

Stintzing Sebastian, Stremitzer Stefan, Sebio Ana, Lenz Heinz-Josef

Abstract excerpt

This article clarifies prognostic and predictive markers in the treatment of colorectal cancer. Multiple chemotherapeutic drugs are approved for metastatic colorectal cancer (mCRC), but available guidelines are often not helpful in directing drug selections. It would be desirable to define patient populations before chemotherapy by biomarkers that predict outcome and toxicities. RAS mutational evaluation remains...

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Source

Identifiers

PMID: 25475572
DOI: 10.1016/j.hoc.2014.09.009

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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