Article
Predictive and prognostic biomarkers with therapeutic targets in advanced colorectal cancer.
World journal of gastroenterology - 14 Apr 2014
Luo Hui-Yan, Xu Rui-Hua
Abstract excerpt
Colorectal cancer (CRC) is one of the most common human malignant diseases and the second leading cause of cancer-related deaths worldwide. The treatment of advanced CRC has improved significantly in recent years. With the emergence of two targeted antibodies, cetuximab (Erbitux), an anti-epidermal growth factor receptor monoclonal antibody and bevacizumab (Avastin), a vascular endothelial growth factor...
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