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Article

Generation and Evaluation of Clade C Simian-Human Immunodeficiency Virus Challenge Stocks

4 Dec 2014

Abstract excerpt

UNLABELLED: The development of a panel of mucosally transmissible simian-human immunodeficiency virus (SHIV) challenge stocks from multiple virus clades would facilitate preclinical evaluation of candidate HIV-1 vaccines and therapeutics. The majority of SHIV stocks that have been generated to date have been derived from clade B HIV-1 env sequences from viruses isolated during chronic infection and typically...

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PMID: 25473043
DOI: 10.1128/jvi.03279-14

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