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Article

Multilocus genetic risk scores for venous thromboembolism risk assessment.

Journal of the American Heart Association - 23 Oct 2014

Soria José Manuel, Morange Pierre-Emmanuel, Vila Joan, Souto Juan Carlos, Moyano Manel, Trégouët David-Alexandre, Mateo José, Saut Noémi, Salas Eduardo, Elosua Roberto

Abstract excerpt

BACKGROUND: Genetics plays an important role in venous thromboembolism (VTE). Factor V Leiden (FVL or rs6025) and prothrombin gene G20210A (PT or rs1799963) are the genetic variants currently tested for VTE risk assessment. We hypothesized that primary VTE risk assessment can be improved by using genetic risk scores with more genetic markers than just FVL-rs6025 and prothrombin gene PT-rs1799963. To this end, we...

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Identifiers

PMID: 25341889
DOI: 10.1161/JAHA.114.001060
PMCID: PMC4323784

Genes

SERPINA10
SERPINC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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