Article
EBUS-TBNA provides highest RNA yield for multiple biomarker testing from routinely obtained small biopsies in non-small cell lung cancer patients - a comparative study of three different minimal invasive sampling methods.
PloS one - 1 Jan 2013
Schmid-Bindert Gerald, Wang Yongsheng, Jiang Hongbin, Sun Hui, Henzler Thomas, Wang Hao, Pilz Lothar R, Ren Shengxiang, Zhou Caicun
Abstract excerpt
BACKGROUND: Multiple biomarker testing is necessary to facilitate individualized treatment of lung cancer patients. More than 80% of lung cancers are diagnosed based on very small tumor samples. Often there is not enough tissue for molecular analysis. We compared three minimal invasive sampling methods with respect to RNA quantity for molecular testing. METHODS: 106 small biopsies were prospectively collected by...
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