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Article

Biomarkers, ketone bodies, and the prevention of Alzheimer's disease.

Metabolism: clinical and experimental - 1 Mar 2015

VanItallie Theodore B

Abstract excerpt

Sporadic Alzheimer's disease (spAD) has three successive phases: preclinical, mild cognitive impairment, and dementia. Individuals in the preclinical phase are cognitively normal. Diagnosis of preclinical spAD requires evidence of pathologic brain changes provided by established biomarkers. Histopathologic features of spAD include (i) extra-cellular cerebral amyloid plaques and intracellular neurofibrillary...

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Identifiers

PMID: 25468143
DOI: 10.1016/j.metabol.2014.10.033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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