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Article

Phenotypic characterization of a novel double knockout PknI/DacB2 from Mycobacterium tuberculosis.

Microbiological research - 1 Jan 2015

Kandasamy Srinivasan, Narayanan Sujatha

Abstract excerpt

Serine/threonine protein kinases play a major role in peptidoglycan biosynthesis in Mycobacterium tuberculosis. To explore the mechanism in detail, in the present study, we have constructed a double knockout (DKO) strain lacking pknI and dacB2 in M. tuberculosis. Initially, we analyzed the colony morphology and found that the DKO strain showed smoother colony morphology on solid agar and irregular shape in...

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Identifiers

PMID: 25467937
DOI: 10.1016/j.micres.2014.10.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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