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Functional and Genetic Characterization of the Tap Efflux Pump in Mycobacterium bovis BCG

10 Jan 2012

Abstract excerpt

Efflux pumps extrude a wide variety of chemically unrelated compounds conferring multidrug resistance and participating in numerous physiological processes. Mycobacterium tuberculosis possesses many efflux pumps, and their roles in drug resistance and physiology are actively investigated. In this work we found that tap mutant cells showed changes in morphology and a progressive loss of viability upon...

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PMID: 22232275
DOI: 10.1128/aac.05946-11

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