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Article

ROS1 immunohistochemistry among major genotypes of non-small-cell lung cancer.

Clinical lung cancer - 1 Mar 2015

Boyle Theresa A, Masago Katsuhiro, Ellison Kim E, Yatabe Yasushi, Hirsch Fred R

Abstract excerpt

BACKGROUND: ROS1 gene fusions cause several cancers by constitutively activating the ROS1 tyrosine kinase receptor. ROS1-targeted inhibitor therapy improves survival in the approximately 1% to 2% of patients with lung adenocarcinoma with ROS1 gene fusions. Although fluorescence in situ hybridizat...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to In Situ Hybridization, Fluorescence

Share to Protein-Tyrosine Kinases

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Source

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Identifiers

PMID: 25467930
DOI: 10.1016/j.cllc.2014.10.003
PMCID: PMC4770803

Genes

ROS1
ALK
EGFR
ERBB2
KRAS
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25467930-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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