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Article

The frequency and impact of ROS1 rearrangement on clinical outcomes in never smokers with lung adenocarcinoma.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Sept 2013

Kim H R, Lim S M, Kim H J, Hwang S K, Park J K, Shin E, Bae M K, Ou S-H I, Wang J, Jewell S S, Kang D R, Soo R A, Haack H, Kim J H, Shim H S, Cho B C

Abstract excerpt

BACKGROUND: To determine the frequency and predictive impact of ROS1 rearrangements on treatment outcomes in never-smoking patients with lung adenocarcinoma. PATIENTS AND METHODS: We concurrently analyzed ROS1 and ALK rearrangements and mutations in the epidermal growth factor receptor (EGFR), and KRAS in 208 never smokers with lung adenocarcinoma. ROS1 and ALK rearrangements were identified by fluorescent in...

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Source

Identifiers

PMID: 23788756
DOI: 10.1093/annonc/mdt220

Genes

ROS1
ALK
EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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