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Article

<i>ROS1</i> Rearrangements Define a Unique Molecular Class of Lung Cancers

4 Jan 2012

Abstract excerpt

PURPOSE: Chromosomal rearrangements involving the ROS1 receptor tyrosine kinase gene have recently been described in a subset of non-small-cell lung cancers (NSCLCs). Because little is known about these tumors, we examined the clinical characteristics and treatment outcomes of patients with NSCLC with ROS1 rearrangement. PATIENTS AND METHODS: Using a ROS1 fluorescent in situ hybridization (FISH) assay, we...

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Identifiers

PMID: 22215748
DOI: 10.1200/jco.2011.35.6345

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