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Article

Enhanced thrombin generation and reduced intact protein S in processed solvent detergent plasma.

Thrombosis research - 1 Jan 2015

Pitkänen Hanna, Jouppila Annukka, Mowinckel Marie-Christine, Lemponen Marja, Patiwael Sanne, Sandset Per Morten, Lassila Riitta, Brinkman Herm Jan M

Abstract excerpt

BACKGROUND: Standardized solvent/detergent (S/D)-treated plasma has been developed as an improved alternative to fresh frozen-plasma (FFP) in the management of severe bleeds. This study aimed at exploring compositional modifications that may influence the general applicability of S/D-treated plasma. MATERIALS AND METHODS: S/D-treated plasma and FFP were compared in procoagulant microparticles and concentration of...

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Source

Identifiers

PMID: 25466844
DOI: 10.1016/j.thromres.2014.10.020

Genes

TFPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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