Article
Analytical considerations for free protein S assays in protein S deficiency.
Thrombosis and haemostasis - 1 Nov 2001
Persson K E, Hillarp A, Dahlbäck B
Abstract excerpt
Protein S is an anticoagulant protein that circulates in plasma in complex with C4b-binding protein (C4BP) or in free form. Deficiency of protein S increases the risk of venous thrombosis. Measurement of free protein S, as compared to total levels, has been shown to be superior for prediction of protein S deficiency. We studied the effects of different handling protocols for an immuno- and a ligand (C4BP)-based...
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