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Article

The molecular basis and clinical significance of genetic mutations identified in myelodysplastic syndromes.

Leukemia research - 1 Jan 2015

Zhang Ling, Padron Eric, Lancet Jeffrey

Abstract excerpt

Myelodysplastic syndromes (MDS) are a heterogeneous cluster of clonal hematopoietic neoplasms manifested by peripheral cytopenias, lineage dysplasia, and a predisposition to acute myeloid leukemia. The pathophysiology of MDS has not been well illustrated. Nevertheless, studies have implicated the MDS phenotype in a broad spectrum of genetic abnormalities. In addition to the known numerical and structural...

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PMID: 25465125
DOI: 10.1016/j.leukres.2014.10.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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