Article
Correlation between plasma DNA and tumor status in an animal model.
PloS one - 1 Jan 2014
Sueoka-Aragane Naoko, Sato Akemi, Kobayashi Naomi, Ide Masaru, Yokoo Masako, Nagano Yumi, Sueoka Eisaburo, Okada Seiji, Kimura Shinya
Abstract excerpt
Overcoming metastasis is one of the most important issues with lung cancer. Since metastasis arises through complex steps, a suitable animal model is indispensable for investigation of metastasis. To establish an animal model reflecting human metastatic lung cancers, we used NOD/SCID/Jak3null (NOJ) mice, which exhibit deficiencies in NK cell activity, macrophage and dendritic cell function, and complement...
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