Article
Tumor DNA circulating in the plasma might play a role in metastasis. The hypothesis of the genometastasis.
1 Oct 1999
Abstract excerpt
BACKGROUND: Clinical and experimental observations suggest that more than one pathway might be involved in the development of metastases. In the present study, we examined the presence of tumor DNA in plasma using an experimental model in which tumor cells were modified with a genome-associated tag. We also investigated whether plasma of tumor-bearing rats had any effect on cultured cells and healthy animals....
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